Naturally Synthetic Inc. is a Canadian research company that develops innovative technologies to enable the efficient synthetic manufacture of rare natural products that are difficult to obtain from plants because of their low natural abundance, requiring complex and costly isolation. A synthetic natural product is molecularly identical to its plant counterpart; the body and science cannot tell the difference. We specialize in making some of nature's most rare prenylated phenolic molecules, including many flavonoids, stilbenes, bibenzyls, chalcones, and several rare non-psychoactive minor cannabinoids. Many of these compounds show promise in pre-clinical and clinical research, but have historically been limited by scarcity. By making these molecules broadly accessible, our researchers at NatSyn are supporting the development of new medicines that can advance human health and well-being.

 

NatSyn was founded in 2021 as a spin-out from McMaster University, originating from a serendipitous discovery in Jakob Magolan’s medicinal chemistry laboratory. In partnership with Peregrine Precision Systems and McMaster University, we produce dozens of rare natural products to make them available to biomedical researchers worldwide, and we continue to refine our proprietary synthesis processes to enable the manufacture of some of these molecules at high purity and large scale.